In a nutshell
- You can spot an ultra-processed product by its ingredients: it contains things you don't use in your kitchen — such as flavourings, emulsifiers or hydrolysed proteins.1
- In a tightly controlled experiment, people ate 500 kcal a day more of them and gained almost a kilo in two weeks.2
- Large observational studies link them to heart disease, type 2 diabetes and anxiety; individual product groups differ, though.4,5
1Four levels of processing
Researchers at the University of São Paulo sorted food into four groups by processing, the NOVA system: unprocessed and minimally processed foods (vegetables, fruit, meat, milk, eggs), culinary ingredients (oil, butter, sugar, salt), processed foods (such as cheese or fresh bread) and ultra-processed products.1
Definition
1 ingredient is enough
A product is ultra-processed when its ingredient list contains at least one substance never used in home cooking —
such as high-fructose corn syrup, hydrogenated fats or hydrolysed proteins — or additives meant to make food tastier
or more appealing: flavourings, flavour enhancers, colours, emulsifiers, sweeteners.1
2The experiments that changed the debate
Moderate evidence
+508 kcal a day
20 adults spent a month at the clinical centre of the US National Institutes of Health (NIH). For two weeks they ate
an ultra-processed diet, for two weeks an unprocessed one — with the same calories, sugar, fat, salt and fibre on the
plate. They could eat as much as they liked. On the ultra-processed diet they ate 508 kcal more a day and gained
0.9 kg; on the unprocessed diet they lost 0.9 kg.2
Moderate evidence
2× more weight lost
In England, 55 people with overweight or obesity twice ate, for 8 weeks each, a diet that followed official
healthy-eating guidelines — once made of minimally processed foods, once of ultra-processed ones. They lost weight on
both, but about twice as much on the minimally processed diet: 2.1% of body weight versus 1.0%.3
3What large studies show
Moderate evidence
9.9 million people
A 2024 review of 45 pooled analyses: more ultra-processed food was linked to 32 of the health outcomes studied. The
most convincing links were with death from cardiovascular disease (50% higher risk), type 2 diabetes, anxiety and
common mental disorders. These are observational studies — association does not mean causation.4
Moderate evidence
+4% mortality
A US study followed more than 114,000 nurses and health professionals for over 30 years. Those who ate the most
ultra-processed food died 4% more often than those who ate the least. The strongest link was with ready-to-eat meat
products such as processed meats; other groups varied.5
What to take from this
- Build your meals mainly on minimally processed foods — vegetables, fruit, legumes, grains, meat, fish, eggs and milk.1
- Read the ingredients: as soon as you see flavourings, emulsifiers or syrups, it is an ultra-processed product.1
- You don't have to avoid them completely. Cutting down on processed meats and meat-based ready meals pays off most.5
- Ultra-processed food is easy to overeat. Log your portions in ForkRep to see how much there really was.2
Sources
Written on , based on studies available at that date. Newer research may change the conclusions.
- Monteiro C. A. et al. (2019). Ultra-processed foods: what they are and how to identify them. Public Health Nutrition 22(5):936–941. doi.org/10.1017/S1368980018003762
- Hall K. D. et al. (2019). Ultra-processed diets cause excess calorie intake and weight gain: an inpatient randomized controlled trial of ad libitum food intake. Cell Metabolism 30(1):67–77.e3. doi.org/10.1016/j.cmet.2019.05.008
- Dicken S. J. et al. (2025). Ultraprocessed or minimally processed diets following healthy dietary guidelines on weight and cardiometabolic health: a randomized, crossover trial. Nature Medicine 31:3297–3308. doi.org/10.1038/s41591-025-03842-0
- Lane M. M. et al. (2024). Ultra-processed food exposure and adverse health outcomes: umbrella review of epidemiological meta-analyses. BMJ 384:e077310. doi.org/10.1136/bmj-2023-077310
- Fang Z. et al. (2024). Association of ultra-processed food consumption with all cause and cause specific mortality: population based cohort study. BMJ 385:e078476. doi.org/10.1136/bmj-2023-078476
This is general information and does not replace a doctor or dietitian. Processing is just one property of food — how much you eat and what it is made of matter too.